刘春法，博士，讲师。中国农业大学博士毕业，中国疾病预防控制中心博士后。2023年8月入职yabo888vip网页版登录，主要研究方向为分枝杆菌流行传播及耐药机制研究。主持国家科技重大专项子课题2项，中国疾病预防控制中心科研项目1项，以第1/共同第1作者发表SCI论文10篇。

主持科研项目情况：

1.国家科技重大专项，2017ZX10304402，2017/01-2020/12，“重大及突发传染病动物模型研制及关键技术研究”课题“重大及突发传染病动物模型关键技术研究”子课题15“结核菌基因分型及耐药基因分析”，77.07万元，结题；

2.国家科技重大专项，2018ZX10103001，2018/01-2021/06，“结核病多重组合诊断技术的多中心评估”课题“肺结核合并真菌感染的分子生物学鉴定以及形态学识别研究”子课题3“肺结核合并真菌菌种形态学鉴定评估”，285.00万元，结题；

3.2018 年度（第二批）中国疾病预防控制中心科研项目，2019/1-2019/12，“我国非结核分枝杆菌流行状况分析及耐药基因预测”47.43万元，结题。

代表性论文：

1.Chunfa Liu, Ruichao Yue, Yang Yang, Yongyong Cui, Lifeng Yang, Deming Zhao, Xiangmei Zhou*. AIM2 inhibits autophagy and IFN-β production during M. bovis infection. Oncotarget. 2016; 7(30):46972-46987. IF=5.168

2.Liu Chunfa, Sun Xin, Li Qiang, Srinand Sreevatsan, Lifeng Yang, Deming Zhao, Xiangmei Zhou*, The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection. Frontiers in Cellular and Infection Microbiology. 2017; 7: 169. IF=3.52

3.Liu CF, Song YM, He WC, Liu DX, He P, Bao JJ, Wang XY, Li YM, Zhao YL. Nontuberculous mycobacteria in China: incidence and antimicrobial resistance spectrum from a nationwide survey. Infect Dis Poverty. 2021 Apr 29; 10(1):59. IF=10.485

4.Yu X, Liu CF, Yang W, Stojkoska A, Cheng G, Yang H, Yue R, Wang J, Liao Y, Sun X, Zhou X, Xie J. Global quantitative phosphoproteome reveals phosphorylation network of bovine lung tissue altered by Mycobacterium bovis. Microb Pathog. 2020 Oct; 147:104402. IF=3.738 (共同一作)

5.Liu CF, Song YM, He P, Liu DX, He WC, Li YM, Zhao YL. Evaluation of Multidrug Resistant Loop-mediated Isothermal Amplification Assay for Detecting the Drug Resistance of Mycobacterium tuberculosis. Biomed Environ Sci. 2021 Aug 20;34(8):616-622. IF=2.831

6.Li H, Liu C, Liang M, Liu D, Zhao B, Shi J, Zhao Y, Ou X, Zhang G. Tuberculosis Outbreak in an Educational Institution in Henan Province, China. Front Public Health. 2021 Oct 12;9:737488. IF=6.461(共同一作)

7.He W, Liu C, Liu D, Ma A, Song Y, He P, Bao J, Li Y, Zhao B, Fan J, Cheng Q, Zhao Y. Prevalence of Mycobacterium tuberculosis resistant to bedaquiline and delamanid in China. J Glob Antimicrob Resist. 2021 Sep;26:241-248. IF=4.349（共同一作)

8.Zhao B, Liu C, Fan J, Ma A, He W, Hu Y, Zhao Y. Transmission and Drug Resistance Genotype of Multidrug-Resistant or Rifampicin-Resistant Mycobacterium tuberculosis in Chongqing, China. Microbiol Spectr. 2022 Oct 26;10(5):e0240521. IF=9.043（共同一作)

9.The CRyPTIC Consortium. Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance mechanisms. PLoS Biol. 2022 Aug 9;20(8):e3001755. IF=9.593（共同一作）

10.The CRyPTIC Consortium. A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics. PLoS Biol. 2022 Aug 9;20(8):e3001721. IF=9.593（共同一作)

11.刘春法, 岳瑞超, 赵德明等. 抗 Mtb 免疫信号通路环鸟甘酸-腺苷酸合成酶-干扰素基因刺激蛋白的研究进展. 中国防痨杂志 2015,37(11): 1160-1163